• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
Inflammation
You are here: Product Lines > Inflammation
 
Toolbar - View Selection
 
 Items 80-100 of 675 Page 5 of 34 Select Page: << 1 2 3 4 5 6 7 8 9 10  >>  
ALX-210-029 Revised 01-Jun-06
Polyclonal Antibody to TRAF2 (mouse) (AR-63)
Add to Clipboard
SYNONYMS anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 2 (mouse) PAb (AR-63)
PRODUCT LINE Inflammation
PRODUCT CATEGORY TRAFs / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-029-R050   50 µl 190.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 250-271 (S250FLEAQASPG
TLNQVGPELLQR271) of mouse TRAF2 (tumor necrosis factor (TNF) receptor-associated factor 2).
SPECIFICITY: Recognizes mouse TRAF2. Detects a band of ~60-64kDa by Western blot.
APPLICATION: Immunoprecipitation (1:50)
Western Blot (1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -80°C.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies: J.M. Zapata, et al.; J. Immunol. 165, 5084 (2000) Abstract; Full Text
General Information
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress • Polyclonal Antibodies • Autophagy Other Products
 
 
ALX-210-030 Revised 30-Oct-06
Polyclonal Antibody to TRAF1 (mouse) (AR-65)
Add to Clipboard
SYNONYMS anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 1 (mouse) PAb (AR-65)
PRODUCT LINE Inflammation
PRODUCT CATEGORY TRAFs / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-030-R050   50 µl 190.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 51-69 (C51RADNLHPVSPGSPLTQEK69) of mouse TRAF1 (tumor necrosis factor (TNF) receptor-associated factor 1).
SPECIFICITY: Recognizes mouse TRAF1. Detects a band of ~50-53kDa by Western blot.
APPLICATION: Immunoprecipitation (1:50)
Western Blot (1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -80°C.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies: J.M. Zapata, et al.; J. Immunol. 165, 5084 (2000) Abstract; Full Text
General Information
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-346 Revised 10-Feb-05
Polyclonal Antibody to MD-1 (human)
Add to Clipboard
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Co-Receptors Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-346-C100   100 µg 267.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
FORMULATION: Purified. Contains 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 112-125 of human MD-1.
SPECIFICITY: Recognizes human MD-1.
APPLICATION: Western Blot
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-352 Revised 30-Oct-06
Polyclonal Antibody to MDA5 (mouse) (AL180)
Add to Clipboard
SYNONYMS anti-Melanoma Differentiation-associated Gene 5 (mouse) PAb (AL180)
anti-Helicard (mouse) PAb (AL180)
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY RNA Helicases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-352-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Contains 0.02% sodium azide.
IMMUNOGEN: Recombinant mouse MDA5 (melanoma differentiation-associated gene 5) (aa 2-208).
SPECIFICITY: Recognizes mouse MDA5.
APPLICATION: Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored as recommended.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Overexpression of Helicard, a CARD-Containing Helicase Cleaved during Apoptosis, Accelerates DNA Degradation: M. Kovacsovics, et al.; Curr. Biol. 12, 838 (2002) Abstract
General Information
MDA5 is a highly conserved helicase whose ATPase activity can be stimulated by RNA and less potently by DNA. It contains two N-terminal CARD domains and a C-terminal helicase domain. The helicase domain, once freed from the CARD domains, then translocates from the cytoplasm to the nucleus where it acts on chromatin architecture. This could allow a more easy access of CAD, thereby accelerating the degradation of genomic DNA.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties: D.C. Kang, et al.; PNAS 99, 637 (2002) Abstract
Related Products
Further Categories Containing This Product:
NF-kB Pathway Other Products • Antiviral Signalling / Related Products • Caspase Recruitment Domain [CARD] Proteins / Related Products • Interferons & Interferon Receptors Other Products • Polyclonal Antibodies
 
 
ALX-210-365 Revised 06-Nov-07
Polyclonal Antibody to PTX3
Add to Clipboard
SYNONYMS anti-Pentraxin 3 PAb
anti-TSG14 PAb
anti-TNF Stimulated Gene-14 PAb
PRODUCT LINE Inflammation
PRODUCT CATEGORY Pentraxin3 [PTX3] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-365-C050   50 µg 370.00 USD Add To Cart
ALX-210-365B-C050 Biotin 50 µg 470.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml
PURITY DETAIL: Affinity purified.
FORMULATION: Liquid. In PBS containing 0.1% sodium azide.
IMMUNOGEN: Recombinant human PTX3.
SPECIFICITY: Recognizes human, mouse, rat  and bovine (weak) PTX3 and chicken homolog PPTX.
APPLICATION: ELISA (detection - excellent): 1:20’000. Use as detection antibody in an ELISA format together with MAb to PTX3 (Prod. No. ALX-804-464 (capture)) and PTX3 standard (Prod. No. ALX-201-124).
Immunocytochemistry
Immunohistochemistry
Immunoprecipitation
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Once thawed store biotinylated antibody at 4°C and do not re-freeze.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes: V.V. Alles, et al.; Blood 84, 3483 (1994) Abstract; Full Text
Expression of a long pentraxin, PTX3, by monocytes exposed to the mycobacterial cell wall component lipoarabinomannan: V. Vouret-Craviari; Infect. and Immunity 65, 1345 (1997) Abstract
PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans: G. Peri, et al.; Circulation 102, 636 (2000) Abstract; Full Text
The long pentraxin Ptx3 is synthesized in IgA glomerulonephritis and activates mesangial cells: B. Bussolati, et al.; J. Immunol. 170, 1466 (2003) Abstract
A secretory-type protein, containing a pentraxin domain, interacts with an A-type K+ channel: D.E. Duzhyy, et al.; J. Biol. Chem. 280, 15165 (2005) Abstract
Pentraxin 3 is elevated in haemodialysis patients and is associated with cardiovascular disease: M. Boehme, et al.; Nephrol. Dial. Transplant. 22, 2224 (2007) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION Sandwich ELISA for PTX3

- 96 well-ELISA  plates (Nunc MaxiSorp 446612) were coated with 100µl of MAb to PTX3 (human) (MNB4) (Prod. No. ALX-804-464), 700ng/ml in 100µl coating buffer (15mM carbonate buffer pH 9.6) and incubated overnight at 4°C.
- After incubation, the plates were washed three times with 300µl/well of washing buffer (PBS + 0.05% Tween 20), and then 300µl of 5% dry milk in washing buffer were added to block non-specific binding.
- The plates were incubated for 2 hours at room temperature and then washed three times with washing buffer.
- 50µl (in duplicate) recombinant human PTX3 standard (Prod. No. ALX-201-124) (75pg/ml to 2.4ng/ml ), cell supernatants or biological fluids diluted in RPMI 1640 + 2% BSA were added and then incubated for 2 hours at 37°C.
- The plates were washed five times with washing buffer, and then 100µl of PAb to PTX3 (human) (Biotin) (Prod. No. ALX-210-365B) 25ng/ml in washing buffer were added in each well.
- The plates were incubated for 1 hour at 37°C and then washed five times with 300µl of washing buffer.
- 100µl/well streptavidin-horseradish peroxidase diluted 1:4'000 were added and the plates incubated for 1 hour at room temperature.
- After incubation the plates were washed 5 times and 100µl of chromogen substrate ABTS were added. Plates were read after 15 minutes at 405nm in an automatic ELISA reader.
Related Products
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-366 Revised 23-Sep-05
Polyclonal Antibody to TIRAP (Pearl-1)
Add to Clipboard
SYNONYMS anti-Toll-interleukin 1 Receptor Domain-containing Adapter Protein PAb (Pearl-1)
anti-Mal PAb (Pearl-1)
anti-MyD88 Adapter-like Protein PAb (Pearl-1)
PRODUCT LINE Inflammation
PRODUCT CATEGORY Toll-IL-1 Receptor Adaptors / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-366-R100   100 µl 290.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Neat serum containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human TIRAP (Mal).
SPECIFICITY: Recognizes human and mouse TIRAP (Mal). Does not cross-react with MyD88.
APPLICATION: Western Blot (1:500)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Product Images
Please click on thumbnails to enlarge.
General Literature References
The Toll-IL-1 receptor adaptor family grows to five members: L.A. O'Neill; Trends. Immunol. 24, 286 (2003)
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-367 Revised 25-Sep-08
Polyclonal Antibody to Toll-like Receptor 3 (mouse)
Add to Clipboard
SYNONYMS anti-TLR3 (mouse) PAb
anti-CD283 (mouse) PAb
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-367-R200   200 µl 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptides corresponding to aa 135-150, 828-844 and 876-891 of mouse TLR3 (Toll-like receptor 3).
SPECIFICITY: Recognizes mouse TLR3. Does not cross-react with human TLR3.
APPLICATION: Flow Cytometry (cell surface & intracellular (1μg/106 cells) (see [2]))
Immunohistochemistry (paraffin sections (1:50), frozen sections (see [1]))
Western Blot (1-3µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 6 months when stored at +4°C.
HANDLING: Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
[1] Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells: P.S. Patole, et al.; J. Am. Soc. Nephrol. 16, 1326 (2005) Abstract
[2] Toll-like receptor-7 modulates immune complex glomerulonephritis: R.D. Pawar, et al.; J. Am. Soc. Nephrol. 17, 141 (2006) Abstract
[3] Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice: P.S. Patole, et al.; Nephrol. Dial. Transplant. 21, 3062 (2006) Abstract
Further Categories Containing This Product:
Antiviral Signalling / Related Products • Polyclonal Antibodies • CD Antibodies
 
 
ALX-210-368 Revised 30-Oct-07
Polyclonal Antibody to Toll-like Receptor 9
Add to Clipboard
SYNONYMS anti-TLR9 PAb
anti-CD289 PAb
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-368-C100   100 µg 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 275-291 of mouse TLR9 (Toll-like receptor 9) (extracellular domain).
SPECIFICITY: Recognizes human and mouse TLR9. Detects a band of ~113kDa by Western blot.
APPLICATION: Flow Cytometry (intracellular (1-2µg/106))
Flow Cytometry (cell surface (see [6]))
Immunocytochemistry (see [5])
Immunocytochemistry (paraffin sections (see [8]); frozen sections (10µg/ml) (see [6]))
Western Blot (0.5-1µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months when stored at +4°C.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
[1] Toll-like receptor 9 regulates tumor necrosis factor-alpha expression by different mechanisms. Implications for osteoclastogenesis: A. Amcheslavsky, et al.; J. Biol. Chem. 279, 54039 (2004) Abstract; Full Text
[2] IFN-gamma overcomes low responsiveness of myeloid dendritic cells to CpG DNA: M. Uchijima, et al.; Immunol. Cell Biol. 83, 92 (2005) Abstract
[3] Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects: I.N. Buhtoiarov, et al.; J. Immunol. 176, 309 (2006) Abstract; Full Text
[4] Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide: L. Chen, et al.; J. Immunol. 177, 2373 (2006) Abstract; Full Text
[5] Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity: M.A. Merrell, et al.; Mol. Cancer Res. 4, 437 (2006) Abstract; Full Text
[6] Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice: P.S. Patole, et al.; Nephrol. Dial. Transplant. 21, 3062 (2006) Abstract
[7] Toll like receptor-9 agonists stimulate prostate cancer invasion in vitro: J.M. Ilvesaro, et al.; Prostate 67, 774 (2007) Abstract
[8] Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation: N. Tran, et al.; ; J. Clin. Endocrinol. Metab. 92, 2773 (2007) Abstract
Further Categories Containing This Product:
Polyclonal Antibodies • CD Antibodies
 
 
ALX-210-369 Revised 30-Oct-07
Polyclonal Antibody to Toll-like Receptor 2
Add to Clipboard
SYNONYMS anti-TLR2 PAb
anti-Toll/Interleukin-1 Receptor-like Gene 4 PAb
anti-TIL4 PAb
anti-CD282 PAb
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-369-C100   100 µg 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
IMMUNOGEN: Extracellular domain of mouse TLR2 (Toll-like receptor 2) (aa 564-580).
SPECIFICITY: Recognizes human and mouse TLR2. Detects a band of ~86kDa by Western blot.
APPLICATION: Western Blot (0.5-2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months when stored at +4°C.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Toll-like receptor 2 and mitogen- and stress-activated kinase 1 are effectors of Mycobacterium avium-induced cyclooxygenase-2 expression in macrophages: S.K. Pathak, et al.; J. Biol. Chem. 279, 55127 (2004) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies • CD Antibodies
 
 
ALX-210-370 Revised 07-Aug-06
Polyclonal Antibody to ABIN-2
Add to Clipboard
SYNONYMS anti-A20-Binding Inhibitor of NF-κB 2 PAb
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY NF-kB Pathway Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart