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ALX-805-066
Revised 11-Apr-07
Monoclonal Antibody to CD137 (mouse) (M4173)
SYNONYMS
anti-4-1BB (mouse) MAb (M4173)
anti-TNFRSF 9 (mouse) MAb (M4173
)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CD137 & CD137L / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-066-C050
50 µg
220.00 USD
ALX-805-066-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
M4173
ISOTYPE:
Rat IgG1
CONCENTRATION:
1mg/ml.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant mouse CD137 (4-1BB).
SPECIFICITY:
Recognizes mouse CD137. Detects a band of ~40kDa by Western blot. Does not cross-react with human CD137.
APPLICATION:
ELISA
Flow Cytometry (1:500)
Western Blot (1:2’000-1:5’000)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-045
Revised 26-Jul-07
Monoclonal Antibody to CD83 (human) (1G11)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-045-C050
50 µg
210.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
1G11
ISOTYPE:
Rat IgG1
CONCENTRATION:
1.9mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.01% sodium azide.
IMMUNOGEN:
Recombinant human CD83 (extracellular domain).
SPECIFICITY:
Recognizes human CD83. The binding affinity strongly increases after deglycosylation of mature DC.
APPLICATION:
Flow Cytometry, Western blot.
Not
inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Do not freeze/thaw.
Product Specific Literature References
The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells
:
M. Lechmann, et al.; J. Exp. Med.
194
, 1813 (2001)
Abstract
;
Full Text
Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies
:
M. Lechmann, et al.; Protein Exp. Purif.
24
, 445 (2002)
Abstract
Further Categories Containing This Product:
Dendritic Cells [DC]
•
Monoclonal Antibodies
ALX-804-325
Revised 03-Nov-08
Monoclonal Antibody to TRAIL (human) (VI10E)
SYNONYMS
anti-Apo-2L (human) MAb (VI10E)
anti-TNFSF 10 (human) MAb (VI10E)
anti-CD253 (human) MAb (VI10E)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
TRAIL [Apo-2L]
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-325-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
VI10E
ISOTYPE:
Mouse IgG2b
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE).
FORMULATION:
Liquid. Purified antibody in PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human soluble TRAIL.
SPECIFICITY:
Recognizes human TRAIL.
APPLICATION:
ELISA
Flow Cytometry
Immunoprecipitation
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored as recommended.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Development, characterization and use of monoclonal antibodies against sTRAIL: measurement of sTRAIL by ELISA
:
N.B. Liabakk, et al.; J. Immunol. Methods
259
, 119 (2002)
Abstract
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-326
Revised 03-Nov-08
Monoclonal Antibody to TRAIL (human) (III6F)
SYNONYMS
anti-APO-2L (human) MAb (III6F)
anti-TNFSF 10 (human) MAb (III6F)
anti-CD253 (human) MAb (III6F)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
TRAIL [Apo-2L]
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-326-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
III6F
ISOTYPE:
Mouse IgG2b
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE).
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human soluble TRAIL.
SPECIFICITY:
Recognizes human TRAIL.
APPLICATION:
ELISA
Flow Cytometry
Immunohistochemistry (frozen sections)
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored as recommended.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Development, characterization and use of monoclonal antibodies against sTRAIL: measurement of sTRAIL by ELISA:
N.B. Liabakk, et al.; J. Immunol. Method.
259
, 119 (2002)
Abstract
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-BC-1130-S
Revised 26-Jan-05
Monoclonal Antibody to Myosin (F113.15F4)
PRODUCT LINE
Cytoskeleton
PRODUCT CATEGORY
Myosin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-BC-1130-S-L001
1 ml
135.00 USD
ALX-BC-1130-S-L005
5 ml
460.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
Others
CLONE:
F113.15F4
ISOTYPE:
Mouse IgG1
FORMULATION:
Liquid. 1ml/5ml of sterile filtered supernatant containing 0.1% sodium azide.
IMMUNOGEN:
Rabbit tibialis muscle.
SPECIFICITY:
Recognizes the N-terminal part (light micromyosin) of fast A and fast B myosin heavy chain in human, rat, bovine, rabbit and other species.
APPLICATION:
Immunohistochemistry (frozen sections, can be used undiluted), Western Blot (dilution 1:20).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Anti-myosin heavy chain monoclonal antibodies reveal two IIB (fast) fiber subtypes:
J.F. Marini, et al.; J. Histochem. Cytochem.
37
, 1721 (1989)
Abstract
Expression of myosin heavy chain isoforms in Duchenne muscular dystrophy patients and carriers:
J.F. Marini, et al.; Neuromuscular Disorders
1
, 397 (1991)
Abstract
Myosin expression in semitendinosus muscle during fetal development of cattle: immunocytochemical and electrophoretic analyses:
J. Robelin, et al.; Repr. Nutr. Development
33
, 25 (1993)
Abstract
General Information
MANUFACTURER
Manufactured by BioCytex.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-BC-1150-S
Revised 17-Oct-08
Monoclonal Antibody to Myosin (F109.3E1)
PRODUCT LINE
Cytoskeleton
PRODUCT CATEGORY
Myosin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-BC-1150-S-L001
1 ml
135.00 USD
ALX-BC-1150-S-L005
5 ml
460.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
CLONE:
F109.3E1
ISOTYPE:
Mouse IgG1
FORMULATION:
Sterile filtered supernatant containing 0.1% sodium azide.
IMMUNOGEN:
Both human ventricular myosin light chains.
SPECIFICITY:
Recognizes human and rat ventricular myosin light chain 2 (LC2) (aa 45-59).
APPLICATION:
Immunohistochemistry (frozen sections, can be used undiluted), Western Blot (dilution 1:10).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
Product Specific Literature References
Probing myosin light chain 1 structure with monoclonal antibodies:
B. Cornillon, et al.; J. Mus. Res. Cell. Motility
13
, 329 (1992)
Abstract
Probing conformational changes within LC2 domains of cardiac myosin:
P. Eldin, et al.; Biochemistry
33
, 12558 (1994)
Abstract
Transmural stretch-dependent regulation of contractile properties in rat heart and its alteration after myocardial infarction:
O. Cazorla, et al.; FASEB J.
19
, 88 (2005)
Abstract
;
Full Text
Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice:
O. Cazorla, et al.; Cardiovasc. Res.
69
, 370 (2006)
Abstract
;
Full Text
Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease:
C. Chimenti, et al.; Am. J. Pathol.
172
, 1482 (2008)
Abstract
Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch:
Y. Ait Mou, et al.; Pflugers Arch.
457
, 25 (2008)
Abstract
General Information
MANUFACTURER
Manufactured by BioCytex.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-BC-3010-S
Revised 26-Jan-05
Monoclonal Antibody to Titin (F146.9B9)
PRODUCT LINE
Cytoskeleton
PRODUCT CATEGORY
Cytoskeleton & Extracellular Matrix Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-BC-3010-S-L001
1 ml
135.00 USD
ALX-BC-3010-S-L005
5 ml
460.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Others
CLONE:
F146.9B9
ISOTYPE:
Mouse IgG1
FORMULATION:
1ml/5ml of sterile filtered supernatant containing 0.1% sodium azide.
IMMUNOGEN:
Purified titin from human skeletal muscle.
SPECIFICITY:
Recognizes human, mouse and rabbit titin.
APPLICATION:
Immunohistochemistry (frozen sections), Western Blot (dilution 1:10).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
General Information
MANUFACTURER
Manufactured by BioCytex.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-520
Revised 31-Oct-06
Monoclonal Antibody to Leptin (human) (HLEP 55G)
SYNONYMS
anti-OB Gene Product (human) MAb (HLEP 55G)
PRODUCT LINE
Obesity & Adipokines
PRODUCT CATEGORY
Leptin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-520-C050
50 µg
195.00 USD
ALX-804-520-C100
100 µg
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
HLEP 55G
ISOTYPE:
Mouse IgG2b
CONCENTRATION:
1mg/ml.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human leptin.
SPECIFICITY:
Recognizes human leptin.
APPLICATION:
ELISA
(direct and indirect: 1:5'000-1:10'000)
Western Blot
(1:5'000-1:10'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-518
Revised 31-Oct-06
Monoclonal Antibody to GITRL (mouse) (MGTL 10)
SYNONYMS
anti-TNFSF 18 (mouse) MAb (MGTL 10)
anti-Glucocorticoid-induced TNF Receptor Ligand (mouse) MAb (MGTL 10)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
GITR & GITRL Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-518-C050
50 µg
220.00 USD
ALX-804-518-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
MGTL 10
ISOTYPE:
Rat IgG2a
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant mouse GITRL.
SPECIFICITY:
Recognizes both natural and recombinant mouse GITRL. Does not cross-react with human GITRL (AITRL).
APPLICATION:
ELISA
(direct and indirect: 1:5’000-1:10’000)
Flow Cytometry (excellent)
(1:1’000)
Western Blot
(1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk; incubate 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells:
H.H. Shin, et al.; Bone
36
, 832 (2005)
Abstract
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-516
Revised 31-Oct-06
Monoclonal Antibody to GITR (mouse) (MGIT 02)
SYNONYMS
anti-TNFRSF 18 (mouse) MAb (MGIT 02)
anti-Glucocorticoid-induced TNFR-related Protein (mouse) MAb (MGIT 02)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
GITR & GITRL Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-516-C050
50 µg
220.00 USD
ALX-804-516-C100
100 µg
290.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
MGIT 02
ISOTYPE:
Rat IgG2a
CONCENTRATION:
1mg/ml.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant mouse GITR.
SPECIFICITY:
Recognizes both natural and recombinant mouse GITR. Does not cross-react with human GITR (AITR).
APPLICATION:
ELISA
(direct and indirect: 1:5'000-1:10'000)
Flow Cytometry (excellent)
(1:1'000)
Western Blot
(1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.)
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
MANUFACTURER
Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-138
Revised 14-Dec-06
Monoclonal Antibody to CD134L (mouse) (blocking) (MGP34)
