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Items 11 of 11
ALX-805-048
Revised 20-Nov-07
Monoclonal Antibody to CD5 (human) (MEM-32)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-805-048-C100
100 µg
195.00 USD
ALX-805-048F-T100
FITC
100 tests
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-32
ISOTYPE:
Mouse IgG1
CONCENTRATION:
MEM-32
: 1mg/ml
PURITY:
MEM-32
: Liquid. In PBS, pH 7.4, containing 15mM sodium chloride.
MEM-32-FITC
: Liquid. In PBS, pH 7.4, containing 15mM sodium chloride and 0.2% BSA.
IMMUNOGEN:
Crude human thymus membrane fraction.
SPECIFICITY:
Recognizes human CD5.
APPLICATION:
Flow Cytometry (20µl per 100µl whole blood or 10
6
cells in suspension)
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
USE/STABILITY:
Purified antibody:
Short term storage at +4°C. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles.
FITC-conjugate:
Store at +4°C. Do not freeze! Protect from light!
Product Specific Literature References
Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen
:
V. Horejsi, et al.; Folia Biol. (Praha)
32
, 12 (1986)
Abstract
Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74):
V. Horejsi, et al.; Folia Biol (Praha)
34
, 23 (1988)
Abstract
Further Categories Containing This Product:
B Cell Receptor [BCR] & Co-Receptors / Related Products
•
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
ALX-804-456
Revised 20-Feb-07
Monoclonal Antibody to LAT (human) (LAT-01)
SYNONYMS
anti-Linker of Activated T Cells (human) MAb (LAT-01)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Adaptor Proteins in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-456-C100
100 µg
240.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
LAT-01
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. Protein A affinity purified antibody in PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant human LAT (linker of activated T cells) cytoplasmic domain.
SPECIFICITY:
Recognizes human LAT. Does not well recognize tyrosine phosphorylated LAT. Does not cross-react with mouse LAT.
APPLICATION:
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
ALX-805-717
Revised 03-Nov-06
Monoclonal Antibody to LAT (LAT-1D1)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Adaptor Proteins in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-805-717-C100
100 µg
240.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
CLONE:
LAT-1D1
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant rat LAT.
SPECIFICITY:
Recognizes mouse and rat LAT. Does not cross-react with human LAT.
APPLICATION:
Western Blot (1:100)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
New monoclonal antibodies recognizing the adaptor protein LAT:
P. Tolar, et al.; Folia Biol. (Praha)
47
, 215 (2001)
Abstract
Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment:
G. Bonello, et al.; J. Cell Sci.
117
, 1009 (2004)
Abstract
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
ALX-804-479
Revised 10-Jun-08
Monoclonal Antibody to Lck (human) (LCK-01)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Kinases in T Cell Signal Transduction / Related Products
Ordering Information
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Format:
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ALX-804-479-C100
100 µg
240.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
LCK-01
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY:
>95% (SDS-PAGE)
FORMULATION:
Liquid. Affinity purified antibody in PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 22-36 of human Lck.
SPECIFICITY:
Recognizes human Lck. Does not cross-react with mouse Lck.
APPLICATION:
Flow Cytometry
Immunocytochemistry
Immunoprecipitation
Western Blot
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Specific Literature References
Incorporation of leucocyte GPI-anchored proteins and protein tyrosine kinases into lipid-rich membrane domains of COS-7 cells
:
M. Cebecauer, et al.; BBRC
243
, 706 (1998)
Abstract
A potential role for protein tyrosine kinase p56(lck) in rheumatoid arthritis synovial fluid T lymphocyte hyporesponsiveness
:
P. Romagnoli, et al.; Int. Immunol.
13
, 305 (2001)
Abstract
;
Full Text
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Src Family Kinases / Related Products
•
Monoclonal Antibodies
ALX-804-809
Revised 24-Mar-05
Monoclonal Antibody to MFG-E8 (mouse) (2422)
SYNONYMS
anti-Milk Fat Globule-EGF Factor 8 (mouse) MAb (2422)
anti-MFGM (mouse) MAb (2422)
anti-Sperm Surface Protein SP47 (mouse) MAb (2422)
anti-MP47 (mouse) MAb (2422)
anti-Lactadherin [Precursor] (mouse) MAb (2422)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Monocytes & Macrophages Other Products
Ordering Information
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Format:
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ALX-804-809-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE:
2422
ISOTYPE:
Hamster Ig
CONCENTRATION:
1mg/ml.
PURITY:
≥95% (SDS-PAGE)
FORMULATION:
Liquid. Purified antibody in PBS containing 0.02% sodium azide.
IMMUNOGEN:
Thioglycollate-elicited mouse peritoneal macrophages.
SPECIFICITY:
Recognizes mouse MFG-E8.
APPLICATION:
Flow Cytometry
Immunoprecipitation
Functional Application (agonistic; increases uptake of apoptotic cells by macrophages and enhances internalization of exosomes by dendritic cells)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Identification of a factor that links apoptotic cells to phagocytes
:
R. Hanayama, et al.; Nature
417
, 182 (2002)
Abstract
Cell biology. Tickling macrophages, a serious business.
:
S. Zullig & M.O. Hengartner; Science
304
, 1123 (2004)
Abstract
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice.
:
R. Hanayama, et al.; Science
304
, 1147 (2004)
Abstract
Expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells.
:
R. Hanayama, et al.; J. Immunol.
172
, 3876 (2004)
Abstract
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
•
Cell Death / Apoptosis / Autophagy Other Products
ALX-804-562
Revised 31-Oct-06
Monoclonal Antibody to SLP-76 (SLP-76/03)
SYNONYMS
anti-SH2 Domain-containing Leukocyte Protein (76kDa) MAb (SLP-76/03)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Adaptor Proteins in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-562-C100
100 µg
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Pig
CLONE:
SLP-76/03
ISOTYPE:
Mouse IgG2b
CONCENTRATION:
1mg/ml
PURITY:
>95% (SDS-PAGE).
PURITY DETAIL:
Protein G affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant human SLP-76 (SH2 domain-containing leukocyte protein (76kDa)) (aa 216-434).
SPECIFICITY:
Recognizes human, mouse and pig SLP-76.
APPLICATION:
Western Blot
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months after receipt when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
ALX-805-716
Revised 03-Nov-06
Monoclonal Antibody to ZAP-70 (human) (ZAP-03)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Kinases in T Cell Signal Transduction / Related Products
Ordering Information
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Format:
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Quantity:
Add To Cart
ALX-805-716-C100
100 µg
225.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
ZAP-03
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY:
≥95% (SDS-PAGE)
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant C-terminal part (160 aa) of human ZAP-70.
SPECIFICITY:
Recognizes human ZAP-70. Detects a band of ~70kDa by Western blot.
APPLICATION:
Flow Cytometry
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Monoclonal Antibodies
ALX-210-827
Revised 18-Oct-07
Polyclonal Antibody to Lck (human)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Kinases in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-210-827-C100
100 µg
320.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
FORMULATION:
Contains 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 38-57 (R
38
NGSEVRDPLVTYEGSNPPA
57
) of human Lck.
SPECIFICITY:
Recognizes human Lck.
APPLICATION:
Immunoprecipitation
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
Product Specific Literature References
The structure of the mu/pseudo light chain complex on human pre-B cells is consistent with a function in signal transduction
:
G.S. Brouns, et al.; Eur. J Immunol.
23
, 1088 (1993)
Abstract
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Src Family Kinases / Related Products
•
Polyclonal Antibodies
ALX-210-566
Revised 31-Oct-06
Polyclonal Antibody to SLP-76 (human)
SYNONYMS
anti-SH2 Domain-containing Leukocyte Protein (76kDa) (human) PAb
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Adaptor Proteins in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
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Quantity:
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ALX-210-566-C100
100 µg
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY:
>95% (SDS-PAGE).
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant human SLP-76 (SH2 domain-containing leukocyte protein (76kDa)) (aa 216-434).
SPECIFICITY:
Recognizes human SLP-76. Other species have not been tested.
APPLICATION:
Western Blot
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months after receipt when stored at +4°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Polyclonal Antibodies
ALX-210-028
Revised 01-Mar-07
Polyclonal Antibody to TRAF6 (Bur 30)
SYNONYMS
anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 PAb (Bur 30)
anti-RING Finger Protein 85 PAb (Bur 30)
anti-Interleukin-1 Signal Transducer PAb (Bur 30)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TRAFs / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-028-R050
50 µl
190.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 451-469 (D
451
AKPELLAFQRPTIPRNPK
469
) of human TRAF6 (tumor necrosis factor (TNF) receptor-associated factor 6). This sequence is completely conserved in mouse TRAF6.
SPECIFICITY:
Recognizes human and mouse TRAF6. Detects a band of ~65kDa by Western blot. Does not cross-react with other members of the TRAF family.
APPLICATION:
Immunohistochemistry (paraffin sections (1:1'000))
Western Blot (1:500-1:2'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -80°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
:
J.M. Zapata, et al.; J. Immunol.
165
, 5084 (2000)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Antiviral Signalling / Related Products
•
Polyclonal Antibodies
ALX-210-572
Revised 03-Nov-06
Polyclonal Antibody to ZAP-70 (human)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
Kinases in T Cell Signal Transduction / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-572-C100
100 µg
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY:
≥95% (SDS-PAGE)
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
IMMUNOGEN:
Recombinant fusion protein corresponding to C-terminal part of human ZAP-70.
SPECIFICITY:
Recognizes C-terminus of human ZAP-70.
APPLICATION:
Western Blot (1:1’000; use standard reducing SDS-sample buffer)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 6 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products
•
Polyclonal Antibodies
