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Viral Signalling
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ALX-630-112 Revised 14-Jan-08
Stachybotrylactam
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SYNONYMS 2-Deoxy Antibiotic F1839A
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
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ALX-630-112-MC05   0.5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C23H31NO4
MW: 385.5
CAS NUMBER: 163391-76-2
SOURCE/HOST: Isolated from Stachybotrys sp. MST-FP1752.
PURITY: ≥95% (HPLC)
APPEARANCE: Light tan solid.
SOLUBILITY: Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Mycotoxin. Immunosuppressive. Weakly inhibits HIV-1 protease.
Product Specific Literature References
Stachybotrys toxins. 1: B.B. Jarvis, et al.; Nat. Toxins 3, 10 (1995) Abstract
Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys Sp. I. Fermentation, isolation and biological activity: B.E. Roggo, et al.; J. Antibiot. (Tokyo) 49, 13 (1996) Abstract
Enantioselective total synthesis and structure revision of spirodihydrobenzofuranlactam 1. Total synthesis of stachybotrylactam: A.S. Kende, et al.; Org. Lett. 5, 1785 (2003) Abstract
Further Categories Containing This Product:
Natural Products - Immunomodulators • HIV / AIDS / Related Products
 
 
ALX-350-317 Revised 08-Apr-08
Tenuazonic acid
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Antitumor Antibiotics
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ALX-350-317-MC05   0.5 mg 150.00 USD Add To Cart
Product Specification
FORMULA: C10H15NO3
MW: 197.3
CAS NUMBER: 610-88-8
MERCK INDEX: 14: 9149
RTECS: UY7425000
SOURCE/HOST: Isolated from Alternaria sp.
PURITY: ≥97% (HPLC)
APPEARANCE: Brown oily solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Antineoplastic compound exhibiting antitumor, antiviral and antibacterial activity. Inhibits protein synthesis by suppression at the ribosome. May act as a mycotoxin.
Product Specific Literature References
Microbial metabolites with insecticidal properties: M. Cole & G.N. Rolinson; Appl. Microbiol. 24, 660 (1972) Abstract
Microbial production of tenuazonic acid analogues: S. Gatenbeck & J. Sierankiewicz; Antimicrob. Agents Chemother. 3, 308 (1973) Abstract
Inhibition of mouse skin tumor promotion by tenuazonic acid: M. Antony, et al.; Cancer Lett. 61, 21 (1991) Abstract
Further Categories Containing This Product:
Antitumor Agents (Anti-proliferative) • Mycotoxins • Antibiotics - Antiviral / Anti-HIV
 
 
ALX-350-296 Revised 30-Jun-08
Thalassiolin B
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products - Antiviral / anti-HIV Agents
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ALX-350-296-MC05   0.5 mg 130.00 USD Add To Cart
Product Specification
FORMULA: C22H22O14S
MW: 542.5
SOURCE/HOST: Isolated from Thalassia testudinum.
PURITY: ≥98% (HPLC)
APPEARANCE: Yellow to green oil.
SOLUBILITY: Soluble in 100% ethanol or DMSO.
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.

Product Description
Inhibitor of HIV cDNA integrase.
Product Specific Literature References
Thalassiolins A-C: new marine-derived inhibitors of HIV cDNA integrase: D.C. Rowley, et al.; Bioorg. Med. Chem. 10, 3619 (2002) Abstract
Further Categories Containing This Product:
Marine Natural Products • HIV / AIDS / Related Products
 
 
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