ALEXIS Biochemicals: Virodhamine . hydrochloride

ALX-340-051

Revised 10-Sep-07

Virodhamine . hydrochloride
SYNONYMS	O-Arachidonoylethanolamine . HCl O-AEA . HCl Arachidonic acid-(2-aminoethyl)-ester . HCl
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Anandamide & Anandamide Analogs

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-340-051-M005		5 mg	126.00 USD

Product Specification

FORMULA:	C₂₂H₃₇NO₂ . HCl
MW:	347.5 . 36.5
CAS NUMBER:	443129-35-9
PURITY:	≥98%
APPEARANCE:	Neat oil.
SOLUBILITY:	Soluble in 100% ethanol, dimethyl formamide or DMSO; also soluble in PBS, pH 7.2.
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	-20°C
LONG TERM STORAGE:	-80°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -80°C. Unstable in solution. Dilute sample and use immediately. We do not recommend storing the aqueous solution for more than one day.

Product Description

Partial agonist with in vivo antagonist activity at the CB₁receptor (EC₅₀=1.9µM; 61% efficacy), full agonist for the CB₂ receptor (100% efficacy).

Product Specific Literature References

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds: T. Sugiura, et al.; J. Biol. Chem. 274, 2794 (1999) Abstract
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor: A.C. Porter, et al.; J. Pharmacol. Exp. Ther. 301, 1020 (2002) Abstract

Further Categories Containing This Product:

Endocannabinoids

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