ALEXIS Biochemicals: W-12 . hydrochloride

ALX-270-155

Revised 04-Mar-05

W-12 . hydrochloride
SYNONYMS	N-(4-Aminobutyl)-2-naphthalenesulfonamide . HCl
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Calmodulin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-155-M005		5 mg	40.00 USD
ALX-270-155-M025		25 mg	160.00 USD

Product Specification

FORMULA:	C₁₄H₁₈N₂O₂S . HCl
MW:	278.4 . 36.5
CAS NUMBER:	89108-46-3
PURITY:	≥98%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in 100% ethanol or water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Antagonist of calmodulin, inhibiting activation of Ca²⁺/calmodulin-dependent phosphodiesterase (PDE I) and myosin light chain kinase.

Product Specific Literature References

T. Tanaka and H. Hidaka; J. Biol. Chem. 255, 11078 (1980) Abstract; Full Text
[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26, 977 (1981) Abstract
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981) Abstract

Further Categories Containing This Product:

Phosphodiesterases / Related Products • Myosin Light Chain Kinase Inhibitors

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