ALEXIS Biochemicals: W-5 . hydrochloride

ALX-270-151

Revised 10-May-05

W-5 . hydrochloride
SYNONYMS	N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Calmodulin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-151-M005		5 mg	20.00 USD
ALX-270-151-M025		25 mg	60.00 USD

Product Specification

FORMULA:	C₁₆H₂₂N₂O₂S . HCl
MW:	306.4 . 36.5
CAS NUMBER:	61714-25-8
PURITY:	≥98%
APPEARANCE:	White to off-white crystalline solid.
SOLUBILITY:	Soluble in water, DMSO, 100% ethanol (hot) or methanol (hot).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 3 years when stored at -20°C. Stock solutions are stable for up to 6 months when stored at +4°C.
HANDLING:	Protect from light.

Product Description

Antagonist of calmodulin, inhibiting Ca²⁺/calmodulin-regulated phosphodiesterase (PDE I) and myosin light chain kinase.

Product Specific Literature References

Hydrophobic regions function in calmodulin-enzyme(s) interactions: T. Tanaka & H. Hidaka; J. Biol. Chem. 255, 11078 (1980) Abstract; Full Text
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981) Abstract
[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26, 977 (1981) Abstract

Further Categories Containing This Product:

Phosphodiesterases / Related Products • Myosin Light Chain Kinase Inhibitors

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