ALEXIS Biochemicals: Z-VD(OMe)VAD(OMe)-FMK

ALX-260-099

Revised 14-Feb-07

Z-VD(OMe)VAD(OMe)-FMK
SYNONYMS	Caspase-2 Inhibitor (Fluoromethylketone)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-099-M001		1 mg	330.00 USD
ALX-260-099-M005		5 mg	988.00 USD

Product Specification

SEQUENCE:	Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone
FORMULA:	C₃₂H₄₆FN₅O₁₁
MW:	695.7
PURITY:	≥99% (TLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Store stock solutions in aliquots at -20°C.
HANDLING:	Keep cool and dry.

Product Description

Irreversible, cell permeable inhibitor of caspase-2.

Product Specific Literature References

Substrate specificities of caspase family proteases: R.V. Talanian, et al.; J. Biol. Chem. 272, 9677 (1997) Abstract; Full Text
Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors: P.A. Gregoli & M.C. Bondurant; J. Cell Physiol. 178, 133 (1999) Abstract
Distinct pathways for stimulation of cytochrome c release by etoposide: J.D. Robertson, et al.; J. Biol. Chem. 275, 32438 (2000) Abstract; Full Text

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