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ALX-260-166 Revised 07-Apr-08 New product
Z-VRPR-FMK
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SYNONYMS Z-Val-Arg-Pro-DL-Arg-FMK . TFA
MALT1 Inhibitor
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Caspase Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-260-166-MC05   0.5 mg 280.00 USD Add To Cart
ALX-260-166-M001   1 mg 520.00 USD Add To Cart
Product Specification
SEQUENCE: Z-Val-Arg-Pro-DL-Arg-fluoromethylketone
FORMULA: C31H49FN10O6 . C2HF3O2
MW: 676.8 . 114.0
PURITY: ≥90% (HPLC)
APPEARANCE: White to slightly yellow powder.
SOLUBILITY: Soluble in water (1mg/ml).
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
Product Description
Inhibits the proteolytic activity of the paracaspase MALT1. MALT1 impairs TCR-induced activation of NF-κB and production of IL-2. It does not affect viability or morphology of cells. The proteolytic activity of MALT1 is key to T cell activation.
Product Specific Literature References
The proteolytic activity of the paracaspase MALT1 is key in T cell activation: F. Rebeaud, et al.; Nat. Immunol. 9, 272 (2008) Abstract
Further Categories Containing This Product:
T Cell Signalling Other ProductsNF-kB Pathway Inhibitors
 
 

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