ALEXIS Biochemicals: cis-9,10-Octadecenamide

ALX-550-121

Revised 06-Feb-08

cis-9,10-Octadecenamide
SYNONYMS	Oleamide ODA
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Sleep-Inducing Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-550-121-M010		10 mg	55.00 USD

Product Specification

FORMULA:	C₁₈H₃₅NO
MW:	281.5
CAS NUMBER:	301-02-0
PURITY:	≥98%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in 100% ethanol, DMSO or dimethyl formamide; poorly soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stock solutions are stable for at least six months when stored at -20°C. Further dilutions of stock solutions in aqueous buffers should be used within 12 hours.

Product Description

Sleep-inducing brain lipid [1]. Shown to be a full CB₁, but not CB₂ receptor agonist [2].

Product Specific Literature References

[1] Chemical characterization of a family of brain lipids that induce sleep: B.F. Cravatt, et al.; Science 268, 1506 (1995) Abstract
[2] Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors: J.D. Leggett, et al.; Br. J. Pharmacol. 141, 253 (2004) Abstract
Structure Determination of an Endogenous Sleep-Inducing Lipid, cis-9-Octadecenamide (Oleamide): A Synthetic Approach to the Chemical Analysis of Trace Quantities of a Natural Product: B.F. Cravatt, et al.; JACS 118, 580 (1996)
Brain lipids that induce sleep are novel modulators of 5- hydroxytrypamine receptors: J.P. Huidobro-Toro & R.A. Harris; PNAS 93, 8078 (1996) Abstract
Inhibition of Oleamide Hydrolase Catalyzed Hydrolysis of the Endogenous Sleep-Inducing Lipid cis-9-Octadecenamide: J.E. Patterson, et al.; JACS 118, 5938 (1996)
Oleamide and anandamide effects on food intake and sexual behavior of rats: D. Martinez-Gonzalez, et al.; Neurosci. Lett. 364, 1 (2004) Abstract
Oleamide: a member of the endocannabinoid family?: C.J. Fowler; Br. J. Pharmacol. 141, 195 (2004), Review Abstract

Further Categories Containing This Product:

Endocannabinoids

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